![]() It's now ready for a fresh start with its next owner. After MacOS has been reinstalled, you'll be greeted by the Setup Assistant, which you can then quit out of and shut down your Mac. (If not, restart your Mac again, holding down Command-R while it reboots.) From the MacOS Utilities window, select Reinstall MacOS and follow the instructions to install the operating system. You should return to the MacOS Utilities window. Install Apples Command Line Developer Tools: xcode-select -install Install MacPorts for your version of the Mac operating system: macOS. (If you don't see the Erase Volume Group button in the lower-left corner, then click the Erase button in the lower-right corner instead.) Next, click the Erase Volume Group and after Disk Utility does its thing, quit Disk Utility. If you are trying to sell an ancient Mac that has a mechanical hard drive instead of a solid-state drive, then choose Mac OS Extended (Journaled) for Format. If you’re reinstalling on a Mac laptop, plug in the power adapter. Why not go with the tried-and-true Macintosh HD? Name: Choose a name for the fresh, new volume.Next, click the Erase button at the top of the Disk Utility window and fill out these two fields: ![]() ![]() Choose Disk Utility, click Continue and select your startup disk - unless you renamed it, odds are it's labeled Macintosh HD or something similar. Type a name for the volume in the Name field, click the Format pop-up menu and choose APFS, then click. In Disk Utility, select the volume you want to erase in the sidebar, then click Erase in the toolbar. In the Recovery app window, select Disk Utility, then click Continue. Next, you'll see the MacOS Utilities window. Choose Apple menu > Restart, then immediately press and hold Command-R.
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Form rounded teaspoons of dough into balls, roll in sugar and place on ungreased baking sheets, Bake at 375 F, 10-12 minutes. If you want a more robust almond flavor, toast the flour in a dry skillet over medium-low heat until golden and fragrant, cool before using. Add flour, sifted with soda and salt mix well. It provides the protein and structure of classic wheat flour while keeping the cookie chewy in the center. Bourbon, Rum, or Brandy can also be used, many vanillas are alcohol-based, and these carry enough flavor to imitate the vanilla.Īnd finally, if you wanted to make these cookies gluten-free I would suggest using almond flour. Vanilla flavored milk, almond or soy, or Maple Syrup. You can sub vanilla extract with one of a couple of things. If you don't have brown sugar on hand, you can make brown sugar by combining 1 cup of white granulated sugar and 1 tablespoon of molasses together in a food processor until combined. If you did want to make this dairy-free, you can substitute shortening for the butter, good old Crisco, or a plant-based shortening, I have used both. I know, I know, but I am a fan of Jif all the way!ĭon't drop the ball on the good ol regular peanut butter for this recipe, Jif is where it's at! They are cookies, after all, none of those words like healthy or healthy-ish here. I make my cookies with crunchy peanut butter, but you could 100% make these with regular if you don't like the peanut pieces in your cookie. Add everything in at the proper stages and gently fold in the flour as the last thing you do. The rest of the process is pretty straightforward. This will ensure you get a perfectly textured cookie. So always be sure to really beat the butter, for at least 3-4 minutes and it begins to get almost white. Overworking the flour can result in a cookie that has a tough texture, and nobody wants that! ![]() She gets a little sciencey with it, but essentially you want to really beat the heck out of your butter and sugar at the beginning of the cooking dough-making process.ĭoing this ensures you get a luxuriously textured cookie, and that when it comes time to add the flour to the mixture you don't have to overwork the flour. It has to do with the beginning stage of making cookies. One tip that I love to share is one that I learned from Christina Tosi. You will have to learn to use different weaponsįor different purposes, also depending on the current mode and map. Mind that although the Assault Rifle has a good TTK value, it also has a high recoil and getting only hitsĬan be pretty hard, especially at medium to high range. Important information is providedīy the TTK (Time to Kill) value, given in milliseconds, assuming all shots are successful hits and the I included screenshots and data about the damage they do,Īmmo and clip capacity, as well as general information about each weapon. "rifle sprinting" and any respectable player uses it, especially in CTF modes.īelow is an overview of the available weapons. Propel yourself or get an extra boost when jumping by firing the weapons. One of the greatest features of AC is the ability to ![]() The knife will also give you two frags instead of one. You can headshot your enemies only with the Sniper Rifle. Or the SMG, since these weapons have a very high recoil and they do the same damage whether you hit your opponent in the leg The head to score a headshot, but in AC it is recommended to aim at the middle part of the body, especially with the Assault Rifle In normal shooters you would usually aim somewhere around the chest or the neck, or even This is why aiming in AC is a bitĭifferent than in other shooters. In AssaultCube, hitting any part of the body will drain the same amount ofīody shot (except for the Sniper Rifle headshot, which instantly gibs an opponent). The last line shows the IP, port and the name of the current server. Since it's a unique ID, you can also use this inįinally, the last column lists the nicknames of the players currently connected to the server. You can use the client number to kick/ban players or to send private messages. This is unique for each player and given when the player joins the server. The cn column lists the player client number. The pj/ping column shows the packet jump delay in milliseconds as well as the actual ping (lag) the player has You get points for scoring with the flag. This is different from the number of frags for various reasons. You can calculate the Kills/Deaths ratioīy dividing the values of the frags and deaths columns. The deaths column shows how many times the respective player died. The total number of frags per team is also For each kill you get aįrag, with the exception of knife kills, which will give you two kills. The frags column tells us how many frags players have, that is, how many kills they did. The first line lists the game mode (in this case TOSOK) as well as the current map and time left on the map. There are two teams, each trying to kill the enemy flag bearer while your own flag is taken by your own team. Every 15 seconds that you keep the flag you will score. There is only one flag and everybody battles for it. KTF (Keep the Flag) and TKTF (Team Keep the Flag) The team with most flags captured in the end wins. The enemy flag and bring it to your own flag to score. ![]() There are two teams, and your team has to capture This is the popular Capture the Flag mode. The team of the last player who survives wins the round. With only the weapon clips and health you get at the beginning of the round. There are no pick-ups in this mode, so you will have to survive The last player who survives wins the game. You get a knife and grenades and have to kill any opponent (FFA). LSS (Last Swiss Standing) and TLSS (Team Last Swiss Standing) You get a pistol, grenades and a knife and have to kill any opponent (FFA). PF (Pistol Frenzy) and TPF (Team Pistol Frenzy) TOSOK is probably the most popular mode for AssaultCube, TOSOK is the same as OSOK, but with teams. With 1 HP and a sniper rifle and have to kill any opponents by hitting them once. This mode is similar to Instagib from other games. OSOK (One Shot One Kill) and TOSOK (Team One Shot One Kill) You get weapons and grenades and have to kill any opponent (FFA). Here is a brief description for each of them:ĭM (Deathmatch) and TDM (Team Deathmatch) ![]() papatasi saliva resulted in protection which was not ascribed to a humoral immune response. Further experiments demonstrated that immunization with PpSP15 (gi|15963509) from P. This protective effect correlated with a strong delayed-type hypersensitivity (DTH) response and an early and increased in situ production of IFN-γ and IL-12. In mice, pre-exposure to saliva completely abrogated the effects of the sand fly saliva and protected the host from disease progression. Alternatively, it could be ascribed to the development of an adaptive immune response that would favor the commitment of a Th2 immunity against Leishmania. The exacerbating effects of saliva may also be related to the early release of epidermal interleukin-4 (IL-4). ![]() Sand fly saliva contains potent antihemostatic and vasodilatator compounds as well as potentially immunomodulatory molecules that can directly down-modulate macrophage effector functions and facilitate the establishment of the infection. The mechanism by which the vector's saliva enhances leishmania infection remains to be clarified. Several observations indicate that sand fly saliva is crucial in the establishment of leishmaniasis and disease pathogenesis –. During parasite inoculation in the host's skin, the vector injects the saliva that contains a large number of pharmacological components –. Leishmania parasites are transmitted to the vertebrate hosts by the bite of sand flies. The disease ranges from asymptomatic infections to self-limiting cutaneous lesion(s) or fatal visceral forms. Leishmaniasis includes a heterogeneous group of diseases that are caused by protozoan parasites of the genus Leishmania. ![]() The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: The project described was supported by the NIH/NIAID Grant Number SP50AI074178. Received: ApAccepted: AugPublished: October 4, 2011Ĭopyright: © 2011 Abdeladhim et al. PLoS Negl Trop Dis 5(10):Įditor: Paul Andrew Bates, Lancaster University, United Kingdom (2011) Human Cellular Immune Response to the Saliva of Phlebotomus papatasi Is Mediated by IL-10-Producing CD8+ T Cells and Th1-Polarized CD4+ Lymphocytes. The latter finding highlights the importance of the identification of the proteins activating the latter lymphocytes in order to develop vaccines based on selected proteins from the saliva of sand flies.Ĭitation: Abdeladhim M, Ben Ahmed M, Marzouki S, Belhadj Hmida N, Boussoffara T, Belhaj Hamida N, et al. Further experiments revealed that the production of IL-10 masked the presence of a second kind of lymphocytes producing IFN-γ, a rather protective cytokine. These data may preclude the protective effect of sand fly saliva pre-exposure in humans. We demonstrated that the immunity against saliva is dominated by the activation of lymphocytes producing a suppressive cytokine called IL-10. Herein we investigated the nature and the importance of the cellular immune response developed against sand fly saliva by individuals at risk of cutaneous leishmaniasis due to Leishmania major. ![]() Data obtained in mice originally indicate that immunization against saliva protected from leishmaniasis supporting possibility that leishmaniasis could be prevented by a vaccine based on sand fly saliva. Sand fly saliva contains several components that increase hemorrhage and interfere with the host's inflammatory response. While probing the skin for a blood meal, vectors salivate into the host's skin. The parasite is transmitted during sand fly bites. Cutaneous leishmaniasis affects millions of people worldwide and is caused by protozoa of the genus Leishmania. ![]() I was curious and started the installation. Here is my advice: Make a backup disk image before you try to install it if you decide to do so. I was given Cubase LE4 with a guitar pedal I bought as a 'freebie'. After all it isn'ty the program, it's the person behind it who makes the difference. Most if not all DAWs on the market nowadays are capable of recording a hit record. ![]() A DAW must meed your needs and you must be comfortable with the workflow. Having said that, the coice of a DAW is however personal. Also all the different ways of routing signals, the ability to work with DAW-controllers and the powerfull tools available (and the GUI) makes Cubase far more usable for me than the other DAWs mentioned. For me Cubase works far more intuitive than PTPA or RB. I use Cubase 5.5 and am completely satisfied with that DAW. I know a lot of people on a homerecording forum that use Cubase LE4 that haven't felt the need to upgrade to the full version. Chances are you won't run into the restrictions at all, at least not for the first year or two. If you decide to invest in an interface to improve your recordings and you get a powerful DAW for free to go with it, why wouldn't you usde it? It saves you money on a DAW (if you don't have one already) and you get a free chance to try out the program. The LE-version of Cubase is a very powerful DAW, even if it doesn't have all the features C5 has. and have suffixes such as "LE" appended to them are worth exactly what you paid for them.Ĭubase, especially, while having a rather large following, is not a very intuitive platform IMHO, hard to learn, hard to set up, hard to keep running from day to day IME. IMO most softwares that come included with things like soundcards, etc. ![]() Definitely a great sweet treat that I could see a hit at any party, whether enjoyed for Happy hour, after dinner, late evening, etc. ![]() ![]() I preferred sipping on mine as it was too yummy to take down in one sip. He added the ingredients over ice in the shaker ( ) and strained into the glasses.Īll four of us LOVED these. Once dinner had come and gone, my hubby grabbed the shot glasses (we use these shot glasses, ,) and rimmed them with cinnamon/sugar. We already had Fireball on hand (have you tried my Fireball Jello Shots yet?!?), so we only had to go to the store for the Rumchata. We were having my parents over for burgers on the grill and what better way to have a sweet treat, than with shots, right?! LOL! When he mentioned it to me a few hours later, I was immediately on board for trying it that evening. We recently stocked up our bar and have been trying new drinks, so he pinned it thinking we would try it later. Try dusting with a mixture of cinnamon and sugar (or nutmeg) on top. Last weekend, my hubby was browsing through Pinterest when he saw a “recipe” for these tasty shots. Mix (or shake) together milk, Baileys Irish Cream and Fireball Whiskey. Wow your guests this weekend with an unexpected twist on the typical brunch menu.Who knew that by adding a little Rumchata with Fireball, you have a combination that is the adult version of Cinnamon Toast Crunch….in shot form! Rejoice in flavors of pastry, not Fireball and Baileys-all courtesy of an adventurous mixologist who dared to combine these unlikely ingredients into one delicious concoction. Start your morning off with a sweet twist! The butterscotch schnapps adds the perfect touch to this unique breakfast shot. Next, pour equal parts of Fireball whisky and RumChata into a shaker filled with ice. ![]() Add a bit of honey to the side of a shot glass, then dip it into your crushed cereal. Use a rolling pin to smash the cereal into a fine crumb. Then press shot glass in cinnamon/sugar mix. Begin by adding some Cinnamon Toast Crunch to a small plastic bag. Dip shot glass in water just a little below rim. Make a toast to French Toast Shots! A unique blend of cinnamon, milk and fried bread flavors offer the perfect combination for an unforgettable shot. (Optional) For Cinnamon rim mix 2 parts cinnamon with 1 part sugar. Combining spicy Fireball whisky, rich Irish cream, butterscotch schnapps and topped off with a banana slice – it’s sure to give you an unforgettable morning experience! Get a unique start to your day and enjoy the flavor of French toast with this delicious shot. What you need to know about the French toast shot Frequently asked questions about toast shots.Toss the fireball into your shaker over your ice. Fill your cocktail shaker up to the top with ice. What you need to know about the French toast shot Gather together your Fireball Whiskey, Rumchata, cinnamon, sugar, shaker, strainer, shot glass and jigger.Create an original concoction using some unexpected ingredients – no champagne, juice or Bloody Mary mix in sight! Jump to: Step out of your comfort zone and start the day off with a unique breakfast cocktail. Get ready to say cheers to breakfast drinks like never before. Spice up your next brunch with a delicious twist – French Toast Shots! Topping classic mimosas, this memorable cocktail combines sweetness and spirit for the perfect morning treat. Indulge in the sweet and savory flavors of breakfast with these delicious pastry-flavored cocktails! Our simple steps make it easy to whip up drinks that complement your morning meal. Looking for a french toast shot recipe? This is the perfect one! Creamy, boozy, spiced, it’s the perfect breakfast shot or morning drink Authors can publish their original stories on other serialization platforms as long as it is not free content on the internet and exists within a paywall.This means the story is no longer exclusive or available as a serialized format on Kindle Vella ever again. Authors can resell their serialized stories as a book if they take it off Vella.Any previously published work cannot be republished even if translated in a different language.The serialized stories shared on the Kindle Vella platform must not be repackaged in another form (book or collection) outside the platform.Authors cannot post content that is public domain or available on the internet for free.Platform authors are not allowed to publish any unoriginal work-that is, work that already exists anywhere else.Although the rules may be updated in the future, these are the current guidelines for using Kindle Vella. Learning them will ensure that your experience with the platform is hassle-free. Several rules govern publishing on Kindle Vella. You can also earn $0.22 from the same story if the reader pays from the 1700-token tier. This price does not include taxes or fees.īased on this, you can earn $0.25 from a 5000-word story if the reader paid for their token from a 200-token tier. This chart helps you understand the amount earned in royalties using the formula above. (number of tokens to unlock episode) * * (50% revenue share) = Earnings per episode This is the calculation format for the royalties. If a reader buys a large number of tokens up front, they get more value. However, the pricing is not as straightforward as it seems. This means when a reader purchases 200 tokens for $1.99 and reads a story with 50 tokens, the author gets $0.25. The authors get 50% of royalties from their stories. A reader may spend 50 tokens to read a 5000-word story and 20 tokens for a 2000-word story. The length of a story determines how many tokens will be needed to read the full story after the free preview. Meanwhile, here's a guide to how much it costs to read KDP serialized stories on the new platform. When releasing this new KDP format, Amazon indicated that the price structure was subject to change. ![]() Interaction between readers and authors is expressed by dropping a "thumbs up" on the stories or adding them to their “faves”.ĭifferent amounts of tokens are needed to unlock episodes based on the length, and authors receive money from their stories based on how many tokens the reader chooses to unlock them with. Storytellers can post stories containing 500 to 6,000 words per episode, and the platform gives readers free access to the first three episodes of any story after which tokens will be needed to continue reading. The stories on the platform are available on the Kindle Vella website for desktop or the Kindle Vella app for iOS or Android. Since it operates on a new KDP format, the Kindle Vella interactive reading tool is different from the already existing Kindle E-reader app. As a bonus, writers can monetize this platform, creating another viable source of passive income. Kindle Vella, like some earlier serialization platforms including Wattpad and Radish, is interactive for authors and readers. ![]() The platform allows authors to publish their stories in little episodes and readers can then have access to these stories by accessing the platform online. Kindle Vella is the latest platform built to host KDP serialized stories. Now, let's get into the details of this novel storytelling platform. This is a major leap for Kindle Direct Publishing (KDP) as they try to gain an even larger share of the fiction reader market. In the same vein, KDP serialized stories are exclusive to the Kindle Vella platform. Serialized stories, if you were wondering, are works of fiction that are released episodically like TV shows and are exclusive to certain platforms. Kindle Vella is a service that allows you to read stories in series. ![]() By learning about and using the platform, you’ll have an edge in modern-day publishing. Amazon finally launched the much anticipated Kindle Vella in July of 2021, but a lot of people are yet to catch on. ![]() It was during his incarceration that be became obsessed with the game, that he devised and perfected his invention. With the help of a fellow prisoner, he was able to have a billiard table installed in his cell. Captain Mingaud, the inventor of the leather cue tip, was imprisoned for political reasons during the French Revolution.Because billiard balls had to be cut from the dead center of a tusk, the average tusk yielded only 3 to 4 balls. The elephants can thank their present existence on the invention of plastics. Before the invention of celluloid and other new-age plastics, billiard balls were made out of ivory.The cost of a game on the first pay-for-play table: one penny. The first coin-operated billiard table was patented in 1903.Billiards was the first sport to have a world championship (1873).In Jefferson's day, billiards was illegal in Virginia (what a scandal!) The dome on Monticello, Thomas Jefferson's home, conceals a billiard room. It has, of course, undergone some perfecting (and some wool/nylon blends are also produced). Wool was used in the 1500's, and remains the fabric of choice today. What is billiard cloth made of? Amazingly, the main component of billiard cloth has remained unchanged for over 400 years. Pool is one of the safest sports in the world (unless you get smacked in the face with the cue ball, that's never fun!). Today, the two terms are used interchangeably. The game of billiards and the pool room became connected in the public's mind. Billiards / pool tables were installed so patrons could pass the time between races. The term "pool room" now means a place where billiards is played, but in the 19th century a pool room was a betting parlor for horse racing. Played there was One-Pocket, which was a table with one pocket and four balls. In 1765 A.D., the first billiard room was built in England. They then killed her, and used the covering of the table to cover her body. The Invaders made a note of forbidding her the use of her billiard table. In 1586, the castle of Mary, Queen of Scots, was invaded and captured. Throughout history, billiards has bridged the gap between the aristocracy and the masses. Players eventually realized this method was far more effective, and the cue as a separate instrument grew out of the maces tail. Since the bulkiness of the mace head made shots along the rail difficult, it was often turned around and the tail end was used. The mace consisted of a curved wooden (or metal) head used to push the ball forward, attached to a narrow handle. Before the cue stick was designed, billiards was played with a mace. The word "cue" is derived from the French queue, meaning tail. Fun Facts About the Game of Pool Pool Historyīilliards (or pool) evolved from a lawn game similar to croquet played sometime during the 15th century in Northern Europe (probably in France). ![]() Photo: Jen Karetnick What to Consider When Choosing the Best Grill Cleanerīefore selecting a new grill-cleaning product to make your grill sparkle, it’s important to determine the type of cleaner you want to use, the application method, and the needed strength of the cleaner so that you don’t accidentally damage the grill grates or any stainless steel surfaces. BEST FAST-ACTING: Goo Gone Grill and Grate Cleaner.BEST NATURAL: Kona Safe/Clean Grill Cleaner.BEST FOR GREASE: Parker & Bailey BBQ Grill Cleaner & Degreaser.BEST FOR GRILL GRATES: Weber Grill Grate Cleaner.BEST FOR GRILL EXTERIORS: Therapy Stainless Steel Cleaner Kit.BEST BANG FOR THE BUCK: Easy-Off BBQ Cleaner.BEST OVERALL: CitruSafe BBQ Grill Cleaner.These grill cleaners below have been proven effective against this stuck-on grease and baked-on food residue, making them among the best on the market and essential for keeping a grill clean. We also tested them on stainless steel surfaces, ceramics, porcelain, and other materials when the makers indicated it was safe to do so. ![]() Where appropriate, we also tried these cleaners on grill accessories like kabob skewers and fish baskets, other outdoor appliances like turkey fryers and smokers, and indoor appliances such as microwaves and ovens. ![]() In short, we made it as challenging as possible for any heavy-duty cleaner. And we casually flung barbecue sauces, oils, honeys, mustards, ketchup, and other condiments on grill exteriors, the inside of hoods, and side burners. We grilled fat by itself to generously coat drip pans. We melted cheese and caramelized sugar in grill baskets to leave crusty coatings. We splashed around extra marinade on grill grates to get a nice sticky char. In addition to simply cooking, we deliberately made some messes. We tested these grill cleaners in real-life situations after cooking a variety of proteins and plant-based dishes. And many just don’t work well, requiring you to scrub just as hard with a grill brush. Unfortunately, some grill cleaners leave behind their own residue that makes users cautious about using them. While most grill chefs will have one or two grill brushes that can quickly clean off most fat or sticky globs of sauce, the best grill cleaner can remove even the most cooked-on grease from your grill grate. Save your stomach the trouble and invest in a grill cleaner that removes rust and baked-on food residue from the grill grate, side burner, hood, and exterior. When sunny skies and warm weather call for cookouts, your grill can quickly get gunked up with grease, fat, sauce, and rust, giving food an unappealing taste or even causing problems in your intestinal tract. Major medical centers across the US, Europe and Asia use iMDsoft technology to improve care quality, ensure patient safety, enhance financial performance, and achieve sustainable market leadership in critical care. IMDsoft is a leading provider of critical care information systems, dedicated to automating local and remote ICUs and peri-operative environments. HIS/RIS, ortho templating options available. Offers image management technology image review, NAS/DAS storage, transmission via intranet/Internet or wireless. MSDS tracking and inventory systems safety management systems.Ī systems integrator of document imaging, data capture, workflow and other enterprise content management solutions (AR/EOBs, AP/invoices, medical records, admissions).Ī pharmaceutical software development company. ![]() Provides hospitals with IT solutions to improve the revenue cycle, streamline registration and scheduling processes, and manage chart deficiencies. Offers outcomes-oriented operations improvement consulting services to healthcare provider organizations.ĭeveloper of ImageNow, providing enterprise document management, imaging and workflow software solutions for healthcare organizations worldwide. Provider of embedded systems and software solutions focusing on real-time embedded applications. Provider of software, services and technologies for healthcare provider organizations.ĪSP for practices and ASCs offering hosted software, outsourcing (A/R management, credentialing, transcription) and consulting services. Provides fingerprint and facial technology for physical and logical security for improved patient confidentiality for hospitals and managed care organizations. Users can graphically represent and drill through information. Provides healthcare organizations dashboard solutions to present real-time information. Systems for storage, retrieval, viewing of large diagnostic files network servers, workstations, flat panel monitors provider software-clinical, HIS and BI. ![]() (IBM Healthcare and Life Sciences Industry)ġ4, 19, 23, 25, 34, 37, 38, 41, 43, 46, 48, 49, 54, 65, 76Į-Business on-demand consulting, services and technology provider for healthcare payers, providers, pharmaceuticals and life science organizations. Referral Management System is designed to increase orders from referring physicians and secure information. Provider of mobile, embedded and workgroup databases that enable anywhere, anytime access to enterprise information. 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